Notes on Lowering Blood Sugar and Improving Insulin


Mark Houston, MD, Notes:



Tocopherols

  • improve INSULIN SENSITIVITY
  • decrease oxidized LDL
  • Inhibit AGE formation

Alpha Lipoic Acid

Flavenoids: quercetin, bilberry, grape seed; chromium

CoQ10

  • reduces HbA1c
  • need ¬†level > 3;

Niacinamide

  • Improve beta-cell function
  • Reduces insulin requirements-dose 25mg/kg;

VitC, Vit B6 100 mg BID, folate

Biotin: 8-16 mg/day

  • Improves insulin sensitivity

Inositol, B12

Potassium: improves Insulin Sensitivity; dose: 100 mEq/d

Selenium:

  • Insulin mimetic
  • Increases GSH
  • Dose 200 mcg/d

Zinc: inc IS 30-50mg/d; manganese incr IS 5-10mg Qday; DHA, EPA, GLA, CLA decr glucose; MUFA (oleic acid, olive oil, etc), carnitine 2 grams BID, inositol 1-3 grams / d, taurine incr IS 1.5-3 grams BID; Glutathione (to incr GSH: NAC, ALA, selenium, whey, vit C, Vit E, pycnogenol, melatonin, bilberry, grape seed extract, resveratrol, tumeric, oral GSH, horse radish, cruciferous vegs, green tea and EGCG; onion and garlic decr glucose

Alcohol less than 1-2 drinks / day

  • U shaped curve… too much alcohol increases glucose

Caffeine: conflicting evidence: avoid or minimal

Cinnamon: decr glucose 18-29%

Note: ARBs (angiotensin receptor blockers: like Benicar decr homocysteine and uric acid); ARBs are good choice in diabetes